Lazio vs Pisa Prediction: Key Stats and Betting Tips

Lazio round off their Serie A campaign at the Stadio Olimpico in Rome on 23 May 2026 with what, on paper, looks like a favourable home assignment against already-doomed Pisa. With mid-table security but little margin for error, the hosts will still want a strong finish to consolidate a top-half position, while the visitors arrive bottom and relegated after a torrid year in the top flight.

The standings underline the contrasting trajectories. Lazio sit 9th with 51 points from 37 matches, perfectly balanced at 39 goals scored and 39 conceded. Pisa, by contrast, are 20th on just 18 points, with a damaging goal difference of -44 after conceding 69 and scoring only 25. For bettors and fans searching for Lazio vs Pisa prediction angles and betting tips, the gap in quality and form is stark.

With Lazio’s home crowd at the Olimpico and Pisa’s form in freefall, this clash shapes up as a chance for the Biancocelesti to put on a statement performance. Pisa, however, did hold Lazio to a 0-0 draw earlier in the campaign, so those looking at Lazio vs Pisa key stats and head-to-head trends will note that the visitors have shown they can frustrate this opponent on their day.

Lazio vs Pisa Key Stats

• Lazio are 9th in Serie A with 51 points from 37 matches, scoring 39 and conceding 39.
• The only recent Serie A meeting between these sides ended Pisa 0-0 Lazio on 30 October 2025 at Arena Garibaldi - Stadio Romeo Anconetani.
• Lazio have kept 15 clean sheets this league season, while Pisa have managed just 5.

Lazio vs Pisa — Tale of the Tape

• Position: 9 vs 20
• Points: 51 vs 18
• Goals For: 39 vs 25
• Goals Against: 39 vs 69
• Clean Sheets: Lazio 15 vs Pisa 5

The season record shows Lazio as a solid, if inconsistent, mid-table side. Their 13 wins, 12 draws and 12 defeats from 37 matches reflect a team that has rarely dominated but has maintained a positive points return and a neutral goal difference. At home, Lazio have taken 27 points from 18 games (7 wins, 6 draws, 5 defeats), scoring 25 and conceding 24 — not spectacular, but respectable.

Pisa’s campaign has been far more problematic. Rooted to 20th with only 2 wins all season, they have lost 23 of 37 matches and conceded 69 goals, an average of 1.9 per game. Away from home they are winless (0 wins, 8 draws, 10 defeats), with 16 goals scored and 43 conceded. Their form line of “DLLLDLDDDDWDLLLDLDLDDLLDLLLLWLLLLLLLL” underlines a side that has struggled badly to compete, particularly in recent weeks.

Lazio vs Pisa Key Matchups

A. Romagnoli vs A. Caracciolo

With no leading scorers data available, defensive leaders could define the pattern. For Lazio, Alessio Romagnoli has been a mainstay at the back, making 31 appearances (30 starts) and logging 2,577 minutes. He has contributed 23 tackles, 19 blocks and 31 interceptions, winning 101 of 168 duels and completing 1,942 passes at an impressive 93% accuracy. Despite picking up 6 yellow cards and 1 red, his presence has underpinned Lazio’s 15 clean sheets.

For Pisa, Antonio Aldo Caracciolo has been equally central, starting 34 of his 35 appearances and playing 3,074 minutes. He has scored 2 goals, taken 20 shots (6 on target) and contributed 71 tackles, 24 blocks and 51 interceptions, while winning 139 of 261 duels. However, his 10 yellow cards highlight how often he has been forced into last-ditch defending in a struggling side. This matchup between experienced centre-backs will be key in set-piece battles at both ends.

M. Zaccagni vs M. Aebischer

In wide and midfield areas, Mattia Zaccagni’s attacking threat contrasts with Michel Aebischer’s all-round industry for Pisa. Zaccagni has made 26 appearances (all starts), scoring 3 goals and registering 27 shots with 14 on target. He has also produced 35 key passes from 773 total passes at 82% accuracy and attempted 60 dribbles, succeeding 23 times. His 82 fouls drawn underline how often he destabilises defences, though he has also collected 6 yellow cards and 1 red.

Aebischer has been Pisa’s workhorse, with 34 appearances (32 starts) and 2,839 minutes. He has 1 goal and 1 assist, 16 shots (5 on target), and has completed 1,490 passes with 33 key passes at 85% accuracy. Defensively, he has 64 tackles and 35 interceptions, but also 44 fouls committed and 8 yellow cards. If Pisa are to disrupt Lazio’s rhythm, Aebischer’s ability to press and recycle possession against Zaccagni’s creativity will be crucial.

Head-to-Head: Last Meetings

The recent head-to-head record is limited but instructive. The only available meeting in this period came in Serie A earlier this campaign, when Pisa managed to shut out Lazio at home. That result shows that despite the gulf in the table, Lazio cannot take this fixture lightly if they lack cutting edge in the final third.

• 30 October 2025: Pisa 0-0 Lazio (Serie A)

Lazio vs Pisa Prediction

Analysis points to a match where Lazio dominate territory and chances against a Pisa side in dire form. Lazio’s league form string of “LLWDW” suggests some recent inconsistency, but their underlying defensive numbers — 39 conceded and 15 clean sheets — are solid. Pisa arrive with “LLLLL” in their last five league games and just 2 goals scored in their last 5 outings in all recent league data, while conceding heavily.

Win probability metrics give Lazio a 45% chance of victory, with a 45% draw probability and only 10% for Pisa. Combined with home advantage and Pisa’s winless away record, the expectation is for Lazio to control proceedings. However, the previous 0-0 draw between these sides and Lazio’s modest scoring rate (1.1 goals per game) suggest this may not be a rout. A professional, controlled home win looks the likeliest outcome.

Predicted Score: Lazio 1-0 Pisa

Lazio League Form

LLWDW

Pisa League Form

LLLLL

Lazio Possible Starting Lineup

A. Furlanetto, Giacomo Giacomone, Nicolo Pannozzo, S. Gigot, Mario Gila, E. Hysaj, A. Marušić, L. Pellegrini, O. Provstgaard, A. Romagnoli, Nuno Tavares, T. Bašić, R. Belahyane, D. Cataldi, F. Dele-Bashiru, V. Farcomeni, M. Lazzari, D. Maldini, N. Rovella, K. Taylor, M. Zaccagni, M. Cancellieri, B. Dia, S. Fernandes, G. Isaksen, T. Noslin, Pedro, A. Przyborek, P. Ratkov, F. Serra.

Lazio have predominantly lined up in a 4-3-3 this season, using that shape in 35 league matches, with occasional switches to 4-2-3-1. The defensive core is built around Romagnoli and Mario Gila, supported by full-backs such as Hysaj, Marušić or Nuno Tavares. In midfield, options like Cataldi, Bašić and Dele-Bashiru offer balance, while in attack Zaccagni, Noslin, Isaksen, Pedro and others provide variety in wide and central roles. However, several key names are unavailable, which could force rotation and opportunities for squad players.

Pisa Possible Starting Lineup

Nícolas, S. Scuffet, A. Šemper, Raúl Albiol, R. Bozhinov, A. Calabresi, S. Canestrelli, A. Caracciolo, F. Coppola, D. Denoon, M. Aebischer, E. Akinsanmiro, B. Bettazzi, J. Cuadrado, M. Højholt, Lorran, F. Loyola, M. Marin, C. Stengs, I. Touré, M. Tramoni, İ. Vural, R. Durosinmi, S. Iling-Junior, M. Léris, H. Meister, S. Moreo, G. Piccinini, F. Stojilković, Tommaso Guizzo, Matteo Luppichini.

Pisa have been tactically flexible, using a 3-5-2 in 20 league games and a 3-4-2-1 in 12, with several other systems tried. That reflects a side searching for solutions in a difficult season. Caracciolo is central to their back line, while Aebischer, Touré and Marin are key in midfield. In attack, options such as Durosinmi, Meister, Iling-Junior and Stojilković provide different profiles. Injuries and suspensions, however, strip away some depth and may force further reshuffles.

Lazio Team News

Lazio are dealing with a substantial absentee list. E. Motta (Injury), Patric (Muscle Injury), I. Provedel (Shoulder Injury), N. Rovella (Red Card), N. Tavares (Yellow Cards), K. Taylor (Yellow Cards) and M. Zaccagni (Knee Injury) are all listed as missing this fixture. That affects the goalkeeping department, defensive options and attacking creativity, and could see rotation in goal and across the back line, as well as changes in midfield and the forward line.

Pisa Team News

Pisa also have multiple concerns. A. Caracciolo (Yellow Cards), F. Coppola (Muscle Injury), D. Denoon (Ankle Injury), Lorran (Inactive) and M. Tramoni (Muscle Injury) are all ruled out, while S. Moreo is questionable with an injury. Losing Caracciolo is a major blow to their defence, and the absence of Tramoni further weakens their midfield options. With Moreo’s status uncertain, their attacking depth could be stretched as well.

Injuries & Suspensions

Lazio:

• E. Motta — Injury
• Patric — Muscle Injury
• I. Provedel — Shoulder Injury
• N. Rovella — Red Card
• N. Tavares — Yellow Cards
• K. Taylor — Yellow Cards
• M. Zaccagni — Knee Injury

Pisa:

• A. Caracciolo — Yellow Cards
• F. Coppola — Muscle Injury
• D. Denoon — Ankle Injury
• Lorran — Inactive
• M. Tramoni — Muscle Injury
• S. Moreo — Injury (Questionable)

Betting Tips: Lazio vs Pisa

Exactly 3 distinct tips from different markets:

• Result Tip: Back Lazio to win. With a 45% implied home win probability versus just 10% for Pisa, plus Lazio’s far superior league position and Pisa’s winless away record, the home side are rightly strong favourites. Across major bookmakers, home odds range from 1.47 (SBO) to 1.61 (1xBet), with several firms like Bet365 and William Hill around 1.55, offering a solid anchor for accumulators.
• Goals Tip: Under 3.5 goals. Lazio average 1.1 goals scored and 1.1 conceded per game, while Pisa average 0.7 scored and 1.9 conceded. Their only recent meeting ended 0-0 on 30 October 2025. With Pisa’s blunt attack and Lazio missing key attackers like Zaccagni, a controlled home win with limited scoring looks likely. While specific under/over odds are not listed here, this angle pairs well with the match-winner market from bookmakers such as 10Bet, Bet365 or Pinnacle.
• Value Tip: Lazio win to nil. Lazio have kept 15 clean sheets this season against Pisa’s total of 25 goals scored in 37 matches and only 5 clean sheets of their own. Pisa have failed to score in 21 league games, including the reverse fixture. Combining Lazio’s defensive solidity with Pisa’s attacking struggles suggests a win to nil could offer value, especially when matched with competitive home-win prices like 1.57 at Marathonbet, Betfair or Pinnacle.

How to Watch Lazio vs Pisa

Broadcast coverage varies by region. General guide:

• Spain: Movistar LaLiga
• UK: Premier Sports
• Australia: beIN Sports
• India: FanCode
• MENA: beIN Sports
• South America: ESPN / Disney+
• Africa: SuperSport

Odds are accurate at the time of writing and subject to change. Please gamble responsibly.